ed to cause amnesia in some situations where it could easily be induced by puromycin or produced an amnesia with a different time course from that of puromycin. Second, puro- mycin was found to inhibit protein synthesis by breaking certain amino-acid chains, and the resulting fragments were suspected of being the actual cause of amnesia in some cases. Third, puromycin was reported to cause abnormalities in the brain, including seizures. Thus, not only were decreased protein synthesis and amnesia dissociated, but alternative mechanisms for the amnestic action of puromycin were readily suggeste
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